St Clement's is home to IMPRINT Church London and predominantly use the church as a community base for youth and students. We have regular youth events and there are Sunday services for youth and students from 5pm.

There has likely been a church at St Clement Eastcheap, located in Candlewick Ward, from at least the eleventh century, probably earlier, and the first reference to the church is found in a deed written in the reign of Henry III (1207–72), which mentions 'St Clement Candlewickstrate'. The church was destroyed in the Great Fire of London of 1666 and its rebuilding has been attributed to Sir Christopher Wren between 1683 and 1687. This seems to be confirmed by the parish account for 1685, which contains the following item: to one third of a hogshead of wine, given to Sir Christopher Wren.